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"What is Neurotoxicity?

"What is Neurotoxicity?

Neurotoxicity occurs when the exposure to natural or manmade toxic substances (neurotoxicants) alters the normal activity of the nervous system. This can eventually disrupt or even kill neurons, key cells that transmit and process signals in the brain and other parts of the nervous system. Neurotoxicity can result from exposure to substances used in chemotherapy, radiation treatment, drug therapies, and organ transplants, as well as exposure to heavy metals such as lead and mercury, certain foods and food additives, pesticides, industrial and/or cleaning solvents, cosmetics, and some naturally occurring substances. Symptoms may appear immediately after exposure or be delayed. They may include limb weakness or numbness; loss of memory, vision, and/or intellect; headache; cognitive and behavioral problems; and sexual dysfunction. Individuals with certain disorders may be especially vulnerable to neurotoxicants.

Is there any treatment?

Treatment involves eliminating or reducing exposure to the toxic substance, followed by symptomatic and supportive therapy.

What is the prognosis?

The prognosis depends upon the length and degree of exposure and the severity of neurological injury. In some instances, exposure to neurotoxicants can be fatal. In others, patients may survive but not fully recover. In other situations, many individuals recover completely after treatment.

What research is being done?

The NINDS supports research on disorders of the brain and nervous system such as neurotoxicity, aimed at learning more about these disorders and finding ways to prevent and treat them. Scientists are investigating the role occupational or environmental toxicants have on progressive neurodegenerative disorders such as Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis, and dementia. Also being studied are the mechanisms that trigger neuroimmune responses in the central nervous system and the possibility that some brain disorders in children may occur when environmental triggers interact with genes.

NIH Patient Recruitment for Neurotoxicity Clinical Trials
At NIH Clinical Center
Throughout the U.S. and Worldwide
Organizations

National Institute of Environmental Health Sciences (NIEHS)
National Institutes of Health, DHHS
111 T.W. Alexander Drive
Research Triangle Park, NC 27709
webcenter@niehs.nih.gov
http://www.niehs.nih.gov
Tel: 919-541-3345

Food and Drug Administration (FDA)
U.S. Department of Health and Human Services
5600 Fishers Lane, CDER-HFD-240
Rockville, MD 20857
http://www.fda.gov
Tel: 301-827-4573 888-INFO-FDA (463-6332)


Prepared by:
Office of Communications and Public Liaison
National Institute of Neurological Disorders and Stroke
National Institutes of Health
Bethesda, MD 20892

NINDS health-related material is provided for information purposes only and does not necessarily represent endorsement by or an official position of the National Institute of Neurological Disorders and Stroke or any other Federal agency. Advice on the treatment or care of an individual patient should be obtained through consultation with a physician who has examined that patient or is familiar with that patient's medical history. "

All NINDS-prepared information is in the public domain and may be freely copied. Credit to the NINDS or the NIH is appreciated.

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Do no harm!

Christianity – “All things whatsoever you would that man should do to you, do you so to them; for this is the law and the prophets.” Mathew 7, (12)
Buddhism – “Hurt not others in ways that you yourself would find hurtful.” (Udana-Varga 5, 8)
Confucianism – “Is there no maxim which ought to be acted upon throughout one’s whole life? Surely, it is the maxim of loving-kindness: Do not unto others what you would not have them do unto you.” (Analects 15, 23)
Hinduism – “This is the sum of duty: do naught unto others which would cause you pain if done to you.” (Mahabharata 5, 1517)
Islam – “No one of you is a believer until he desires for his brother that which he desires for himself.” (Sunnah)
Judaism – “What is hateful to you; do not to your fellowman. That is the entire Law; all the rest is commentary.” (Talmud, Shabbat 3 id)
Taoism – “Regard your neighbor’s gain as your own gain, and your neighbor’s loss as your own loss.” (Tai Shang Kan Yin P’ien)
Zoroastrianism – “That nature alone is good which refrains from doing another whatsoever is not good itself.” (Dadisten-I-dink, 94, 5)
Treating others the way we want to be treated ensures that this can help our soul to reach spiritual maturity. We must teat the other sentient being as though we are that being. What treatment can you expect from a worm you are about to step on, or a tree that is about to be cut down? Instead, view that other being as though you are it, and then treat it the way you expect to be treated from that standpoint. We lay out the events along our own journey to spiritual completeness through the practice of our humanness.
More and more, especially in the Western world, people are becoming dependant on others for one or another thing. A person may blame his therapist for the lack of progress, another may blame his lawmakers for the way their decisions have affected his life directly or indirectly. Another may blame his childhood and his parents by seeing them as the contributors to the flaws in his character today. A criminal may blame the justice system for not providing enough comfort while in prison; the list goes on. In fact, we are responsible for all of our emotions, thoughts and behaviors. Yes, we do not live an isolated life and come in contact with others all of the time, but eventually we are the ones that are fully responsible for our own moral and spiritual attitude. In the New Testament, we read that Jesus healed a man who had been sick for thirty-eight years. After he was healed, Jesus instructed him “Listen, you are well now; so stop sinning or something worse may happen to you” John 5-14. This example shows us that we ourselves can hurt our physical, mental, and spiritual well-being through the nature of our actions.
A person that is spiritually mature realizes that no one is to blame for the unpleasant events in his life. Such a person acknowledges that everything in nature is connected and that sooner or later as the popular layman’s saying goes: “What goes around comes around.” The law of cause and affect does not apply only to our actions towards others, but it holds true regarding our thoughts, feelings, and behavior in general.

Excerpt from: Guru in Jeans: Inward Journey to Psychospiritual Awakening.